Exclude testicular torsion if presents with significant groin pain. Henochschonlein purpura hsp, also known as iga vasculitis, is a disease of the skin, mucous membranes, and sometimes other organs that most commonly affects children. Henochschonlein purpura, nephritis, therapy, children introduction henochschonlein purpura hsp is an immunologically mediated disease associating purpura plus. Henoch schonlein purpura hsp is a disease involving inflammation of small blood vessels. The condition causes inflammation swelling of small blood vessels.
Background 1st described in 1801 by william heberden, a physician in. Henoch schonlein purpura associated with bee sting. Henochschonlein purpura, sometimes known as hsp, is an autoimmune condition that causes inflammation in the tiny blood vessels of the skin. Henoch schonlein purpura hsp is a systemic vasculitic disease which is common in. Abdominal symptoms occur in 70% of cases, with possible intussusception or intestinal perforation. Jul 24, 2019 henoch schonlein purpura also known as iga vasculitis is a disorder that causes the small blood vessels in your skin, joints, intestines, and kidneys to become inflamed and bleed. In the skin, the disease causes palpable purpura small, raised areas of bleeding underneath the skin, often with joint pain and abdominal pain.
Henochschonlein purpura hsp is a vasculitis inflammation of blood vessels that affects small blood vessels mainly in the skin, intestines, and kidneys. Others gi haemorrhage, bowel ischaemia, necrosis or perforation, proteinlosing enteropathy and pancreatitis. Henochschonlein purpura is common in children between the ages of two and 10. Urological manifestations of henochschonlein purpura. The characteristic pathological feature of this vasculitis is iga immune complex deposition in vascular walls of the affected organs. It is not clear what triggers the condition, but it often appears a few weeks after an upper respiratory infection such as strep or mycoplasma. Hsp is most common in younger pts clinical red maculopapules on legs and buttocks. This disease is mainly characterized by palpable purpura, arthritis arthralgia, abdominal pain, and kidney. Henoch schonlein purpura is a vasculitis usually with a benign course. Henochschonlein purpura hsp is the most common vasculitis in children, affecting 8 to 20 children per 100 000 annually. Henochschonlein purpura hsp is a systemic vasculitis.
In describing hsp, heberden wrote of a 5yearold boy who was seized with pains and swellings in various parts. Henoch schonlein history henoch schonlein purpura support. Henochschonlein purpura anaphylactoid purpura, vascular purpura internal medicine an acquired form of small vessel vasculitis with igadominant immune deposits affecting small vesselsarteries, capillaries, venules, typically of the skin, gut, and glomeruli, associated with arthralgia andor arthritis. Dec 10, 2018 the vast majority of people with henoch schonlein purpura hsp recover on their own within several weeks. Nov 25, 2015 background henochschonlein purpura hsp or anaphylactoid purpura. Original article risk factors for renal damage in henochschonlein. Risk factors, renal damage, henochschonlein purpura. Henochschonlein purpura associated with celiac disease. Henochschonlein purpura symptoms and causes mayo clinic. Henochschonlein purpura is the most common childhood vasculitis, but may also affect adults.
Henochschonlein purpura is a small vessel vacuities in which complexes of immunoglobulin a iga and complement component 3 c3 are deposited on arterioles. The inflammation causes blood vessels in the skin, intestines, kidneys, and joints to start leaking. Hemorrhagic bullous lesions in a girl with henoch schonlein purpura. Jul 10, 2015 henoch schonlein purpura hsp, also referred to as immunoglobulin a iga vasculitis, is an immunemediated systemic vasculitis commonly found in males between the ages of two and eleven 1,2. Henoch schonlein purpura hsp is an immunemediated vasculitis. Henochschonlein purpura hsp, also called immunoglobulin a. Henochschonlein purpura hsp is an immunemediated vasculitis. Therapy for children with henochschonlein purpura nephritis. Schonlein purpura nephritis hspn through february 2015.
Frequently, hsp leads to abdominal pain and intestinal bleeding, renal involvement and joint pain. Henoch schonlein purpura, nephritis, therapy, children introduction henoch schonlein purpura hsp is an immunologically mediated disease associating purpura plus urticaria, characteristically affecting lower limbs, buttocks, and elbows. Henochschonlein purpura hsp, also referred to as immunoglobulin a iga vasculitis, is an immunemediated systemic vasculitis commonly found in males between the. Henochschonlein purpura in children trnka 20 journal of. Caso clinico trinidad hasbuna,b, ximena chaparroa,b, viera kaplanc, felipe cavagnarod, alex castroe apediatric dermatology department, pediatric service, dr. Henoch schonlein purpura, sometimes known as hsp, is an autoimmune condition that causes inflammation in the tiny blood vessels of the skin. Exequiel gonzalez cortes hospital, santiago, chile. Symptoms can begin in children, most commonly between the ages of 4 and 7 years, soon after an upper respiratory tract infection or a streptococcal pharyngitis sore throat infection. Henoch schonlein purpura phs, also called iga vasculitis, is the most common systemic vasculitis in childhood, although it can also occur in adults. The history of henoch schonlein started with dr william heberden, a london physician, described the first cases of henoch schonlein hee. Hsp presents with purple spots on the skin purpura, arthralgia, digestive problems, and kidney injury.
He x, yu c, zhao p, ding y, liang x, zhao y, et al. Cyclosporine a csa versus methylprednisolone pulses mp in the treatment of severe henochschonlein purpura. Pdf henochschonlein purpura hsp is the most common vasculitis of childhood. Trapani s, micheli a, grisolia f, resti m, chiappini e. Background 1st described in 1801 by william heberden, a physician in london, who wrote about a case of a 5 year old boy with hematuria, abdominal pain, joint pains and skin rash. Poststaphylococcal infection henochschonlein purpura nephritis. Henochschonlein purpura germany pdf ppt case reports. Severe hemorrhagic bullous lesions in henoch schonlein purpura. The most striking feature of this form of vasculitis is a purplish rash, typically on the lower legs and buttocks. The inflammation causes blood vessels in the skin, intestines. Pitfalls in recommending evidencebased guidelines for a protean disease like henochschonlein purpura nephritis. The role of corticosteroid in hemorrhagic bullous henoch schonlein purpura. Henochschonlein purpura is a vasculitis usually with a benign course.
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